lose hope; beyond hope；disappointed；let down。
例句：
用作名詞 (n.)
1、Not getting an invitation to the party is a big letdown for Jill.
2、To some, the apparent limitations of quantum computers might come as a letdown.
或許會有些人認為，量子電腦明顯的侷限真是令人失望。
3、醫生們對他的痊癒失望了。The doctors could hold out no hope of his recovery.
4、你本應該接受那個的，我對你很失望。You should have accepted that. I"m disappointed in you.
5、我會努力工作，我不想讓他失望。I"ll work hard. I don"t want to let him down
6、我們清楚明白地表達了我們的失望、傷心和憤怒。We expressed in the clearest possible way our disappointment, hurt and anger
7、我們等了21年了，如今不要讓我們失望。We waited twenty-one years, don"t fail us now.
8、這是她第一次感受到失望。This is the first time she has experienced disappointment
9、我們覺得已經受夠了失望和情緒困擾。We feel that we have had our fill of disappointments and emotional upsets.
10、你做那樣的事使我太失望了。You let me down doing a thing like that.
11、出問題時，我們大家自然都感到失望和沮喪。When things go wrong, all of us naturally feel disappointed and frustrated
13、我對已發生的一切感到極其失望。I feel absolutely dreadful about what has happened.
詞義辨析
despair，desperation，depression，disappointment
這些名詞都有“絕望、沮喪”之意。
1、despair普通用詞，指因災難等因素而喪失希望和信心，陷入沮喪，絕望的境地。
2、desperation語氣強烈，指因絕望而使人採取無所顧忌的瘋狂行動。
3、depression側重指因遭受重大失利或挫折而產生的低落情緒。
4、disappointment多指願望或期望的落空。
lose hope; beyond hope；disappointed；let down。
例句：
用作名詞 (n.)
1、Not getting an invitation to the party is a big letdown for Jill.
2、To some, the apparent limitations of quantum computers might come as a letdown.
或許會有些人認為，量子電腦明顯的侷限真是令人失望。
3、醫生們對他的痊癒失望了。The doctors could hold out no hope of his recovery.
4、你本應該接受那個的，我對你很失望。You should have accepted that. I"m disappointed in you.
5、我會努力工作，我不想讓他失望。I"ll work hard. I don"t want to let him down
6、我們清楚明白地表達了我們的失望、傷心和憤怒。We expressed in the clearest possible way our disappointment, hurt and anger
7、我們等了21年了，如今不要讓我們失望。We waited twenty-one years, don"t fail us now.
8、這是她第一次感受到失望。This is the first time she has experienced disappointment
9、我們覺得已經受夠了失望和情緒困擾。We feel that we have had our fill of disappointments and emotional upsets.
10、你做那樣的事使我太失望了。You let me down doing a thing like that.
11、出問題時，我們大家自然都感到失望和沮喪。When things go wrong, all of us naturally feel disappointed and frustrated
13、我對已發生的一切感到極其失望。I feel absolutely dreadful about what has happened.
詞義辨析
despair，desperation，depression，disappointment
這些名詞都有“絕望、沮喪”之意。
1、despair普通用詞，指因災難等因素而喪失希望和信心，陷入沮喪，絕望的境地。
2、desperation語氣強烈，指因絕望而使人採取無所顧忌的瘋狂行動。
3、depression側重指因遭受重大失利或挫折而產生的低落情緒。
4、disappointment多指願望或期望的落空。