1.have trouble（ in 可以省略）doing sth 在做某事方面有困難, 費事，後面習慣接動名詞作賓語

I have some trouble (in) reading the letter，for handwriting is very bad.

我讀這封信很困難, 因為他的書寫很差.

With the boy leading the way,we had no trouble finding the village.

由於有那個男孩領路，我們沒費多大勁就找到了那所村莊。

2.have trouble with sth有病痛, 因…苦惱;在某方面有麻煩，後面習慣接名詞、代詞，名詞性短語

She is having trouble with her teeth.

她牙齒痛.

He has some trouble with his English pronunciation.

他的英語發音有問題。

同…鬧糾紛

We had trouble with our neighbors over the noise that they were making.

我們因鄰居製造的噪音而與他們鬧糾紛.

祝你學習進步,開心如意！