speak with 和speak to 多數時候可以通用，但有時意思略有不同，

speak to傾向於單向講話，有時帶有指示、責備的意思，而speak with

強調你來我往，雙向交流。

speak with

英 [spi:k wi餧 美 [spik wj餧

和…談話，和…商量

例句

1.She says she must speak with you at once

她說她必須立刻跟你談談。

2.I need to speak with her right this minute

我現在就需要跟她談談。

speak to

英 [spi:k tu:] 美 [spik tu]

對…講;圍繞…談;責備;提醒

例句

1.If they don"t want to speak to me, fine. No problem.

如果他們不想和我講話，好的。我不介意。

2.I must speak to Tania at once

我要馬上跟塔尼婭講話。