1、意思上的區別：
make jokes about：講笑話，開玩笑。
make jokes on：拿…開玩笑。
2、用法區別
make jokes about後面一般接something（某件事）。
make jokes on後面一般接somebody（某人）。
3、例句：
①、make jokes about
They often make jokes about my bald head.
他們常拿我的禿頂開玩笑。
Don"t laugh at, stare at or make jokes about disabled people.
不要嘲笑，盯著或是拿殘疾人開玩笑。
They make jokes about the way I wear glasses.
他們取笑我戴眼鏡的樣子。
②、make jokes on
I could just laugh loudly and make jokes on someone who can accept certain degree of humor.
我可以盡情地大笑，盡情地開玩笑，因為那些人不會因為一些小事就和我絕交。
https://iknow-pic.cdn.bcebos.com/9c16fdfaaf51f3de66e43e2899eef01f3a29792c
擴充套件資料
同義句型解析：
crack a joke
打哈哈；調謔；講笑話，開玩笑。
例句：
But relates the good colleague also mutually to crack a joke.
但私下關係好的同事也互相開玩笑。
Asks you to tell me, our calculates anything, if you do not love me, please do not take me to crack a joke, I do not like.
請你告訴我，我們這算什麼，要是你不愛我，請你不要拿我開玩笑，我不喜歡。
1、意思上的區別：
make jokes about：講笑話，開玩笑。
make jokes on：拿…開玩笑。
2、用法區別
make jokes about後面一般接something（某件事）。
make jokes on後面一般接somebody（某人）。
3、例句：
①、make jokes about
They often make jokes about my bald head.
他們常拿我的禿頂開玩笑。
Don"t laugh at, stare at or make jokes about disabled people.
不要嘲笑，盯著或是拿殘疾人開玩笑。
They make jokes about the way I wear glasses.
他們取笑我戴眼鏡的樣子。
②、make jokes on
I could just laugh loudly and make jokes on someone who can accept certain degree of humor.
我可以盡情地大笑，盡情地開玩笑，因為那些人不會因為一些小事就和我絕交。
https://iknow-pic.cdn.bcebos.com/9c16fdfaaf51f3de66e43e2899eef01f3a29792c
擴充套件資料
同義句型解析：
crack a joke
打哈哈；調謔；講笑話，開玩笑。
例句：
But relates the good colleague also mutually to crack a joke.
但私下關係好的同事也互相開玩笑。
Asks you to tell me, our calculates anything, if you do not love me, please do not take me to crack a joke, I do not like.
請你告訴我，我們這算什麼，要是你不愛我，請你不要拿我開玩笑，我不喜歡。