1. In the end的相對片語是at first.The opposite of in the end is usually

例句如下：

At first we didn’t get on very well, but in the end we became good friends.

起初我們相處並不是很好，但最後我們成了好朋友。

2. 容易記混的是At the end

At the end (of something) = at the time when something ends.

例句：

at the end of the month

at the end of January

at the end of the game

at the end of the film

at the end of the course

at the end of the concert

I’m going away at the end of January / at the end of the month.

At the end of the concert, there was great applause.

The players shook hands at the end of the game.

You cannot say ‘in the end of …’. So you cannot say ‘in the end of January’ or ‘in the end of the concert’.

The opposite of at the end (of …) is (of …):

I’m going away at the beginning of January.

一月初我就要離開了。