depend on側重在依靠、取決於；rely on側重在信任、依賴。可以透過下面的一些例句來了解它們之間用法的區別：
一、depend on / upon
“依賴”、“依靠”、“指望”、“ 取決於”。普通用語，使用較廣，指憑藉或依靠某人或某物的支援和幫助才能生存或成功.
1、All living things depend on / upon the sun for their growth.
萬物靠太陽生長。
2、anguage not only depends on / upon its culture, but in turn structures reality for this culture.
語言不僅依賴其文化，而且還反過來為這文化構建現實。
3、Human behavior is mostly a product of learning, while the behavior of an animal depends mainly on / upon instinct.
人類的行為通常是後天學習的產物，而動物的行為主要取決於本能。
二、rely on / upon
這個動詞短語側重指“相信”或“依賴”、“依靠”某人或某物。也可以表示 “指望”。
1、he manufacturers should rely on / rest on the advance in technology and the superb quality of after-sale service to win the customers in the market.
生產廠家應該依靠科技進步和一流的售後服務贏得了國內外眾多使用者的市場。
2、Charities rely on / rest on voluntary donations or contributions.
慈善事業依靠自願捐贈。
3、You can rely on / rest on me to keey your secret.
你儘管相信我一定為你保密。
4、You can"t rely on / rest on for assistance. He is no so dependent as you think.
你不能指望他來幫助你。他並不像你想象那樣值得依賴。
depend on側重在依靠、取決於；rely on側重在信任、依賴。可以透過下面的一些例句來了解它們之間用法的區別：
一、depend on / upon
“依賴”、“依靠”、“指望”、“ 取決於”。普通用語，使用較廣，指憑藉或依靠某人或某物的支援和幫助才能生存或成功.
1、All living things depend on / upon the sun for their growth.
萬物靠太陽生長。
2、anguage not only depends on / upon its culture, but in turn structures reality for this culture.
語言不僅依賴其文化，而且還反過來為這文化構建現實。
3、Human behavior is mostly a product of learning, while the behavior of an animal depends mainly on / upon instinct.
人類的行為通常是後天學習的產物，而動物的行為主要取決於本能。
二、rely on / upon
這個動詞短語側重指“相信”或“依賴”、“依靠”某人或某物。也可以表示 “指望”。
1、he manufacturers should rely on / rest on the advance in technology and the superb quality of after-sale service to win the customers in the market.
生產廠家應該依靠科技進步和一流的售後服務贏得了國內外眾多使用者的市場。
2、Charities rely on / rest on voluntary donations or contributions.
慈善事業依靠自願捐贈。
3、You can rely on / rest on me to keey your secret.
你儘管相信我一定為你保密。
4、You can"t rely on / rest on for assistance. He is no so dependent as you think.
你不能指望他來幫助你。他並不像你想象那樣值得依賴。