dat_h= int16(123);

dat_l= int16(-321);

if dat_h >= 0

dat_h_bin = dec2bin(dat_h,16);

else

dat_h_bin = dec2bin(2^16-dat_h,16);

end

if dat_l >= 0

dat_l_bin = dec2bin(dat_l,16);

else

dat_l_bin = dec2bin(2^16-dat_l,16);

end

if dat_h >= 0

dout = single(bin2dec([dat_h_bin,dat_l_bin]));

else

dout = single(2^32 - bin2dec([dat_h_bin,dat_l_bin]));

end